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PubMed — User Guide

Biomedical literature database.

Strengths
  • Collection of 35 million+ life sciences and medical papers
  • Completely free, no registration required
  • The most authoritative, maintained by the U.S. National Library of Medicine
  • Advanced search functionality is powerful
  • Free full text of a large number of papers (PubMed Central)
Best for
  • Medical and life sciences literature search
  • Clinical research evidence query
  • Review of research on drugs and treatments
  • medical education and learning
  • public health research

Efficient search techniques

Master the search syntax of PubMed to accurately find the documents you need.

Scenario

Exact search using MeSH terms

Prompt example
PubMed uses MeSH (Medical Subject Headings) to standardize terms:

Basic search:
"diabetes mellitus type 2 AND metformin"

Advanced search tips:
1. Qualified fields:
   "CRISPR[Title]" - search for title only
   "Smith J[Author]" - Search for a specific author

2. Limit document types:
   Select in Filters:
   - Randomized Controlled Trial (RCT)
   - Systematic Review
   - Meta-Analysis

3. Limited time:
   Select the publication year range in Filters

4. Only read the full text:
   Check "Free full text"
Output / what to expect
Find the target document accurately, Avoid interference from irrelevant results, High-quality document type screening improves retrieval efficiency.
Tips

Using MeSH terms is more precise than ordinary keyword searches and allows you to look up standard terms in the MeSH database.

Scenario

Use PubMed advanced search

Prompt example
Click "Advanced" to enter advanced search:

Build complex queries:
- Field: Select Title/Abstract/MeSH Terms, etc.
- Logic: AND/OR/NOT
- Add multiple search criteria

Example:
(("artificial intelligence"[Title/Abstract])
AND ("medical diagnosis"[MeSH Terms]))
AND (2020:2025[Publication Date])

Search history:
Previous searches can be saved and combined
Output / what to expect
Build precise complex queries, Find documents that meet all criteria, Search history for easy reuse.
Tips

Queries constructed from advanced searches can be saved to facilitate periodic updates to the literature search.

Starter & above

The rest of this guide

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